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(Q21101916)
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English
Rho guanine nucleotide exchange factor 15
mammalian protein found in Homo sapiens
E5
ephexin-5
Vsm-RhoGEF
Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF15
rho guanine nucleotide exchange factor 15
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O94989
part of
Dbl homology (DH) domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O94989
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O94989
Dbl homology (DH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O94989
encoded by
ARHGEF15
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O94989
molecular function
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IPI
GTPase activator activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
guanyl-nucleotide exchange factor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
cell component
cytoplasm
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
ISS
dendrite
determination method
ISS
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
cell projection
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
biological process
regulation of Rho protein signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
regulation of catalytic activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IDA
retina vasculature morphogenesis in camera-type eye
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
positive regulation of stress fiber assembly
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
ISS
negative regulation of synapse maturation
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O94989
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
positive regulation of GTPase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94989
determination method
IEA
has part(s)
Dbl homology (DH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O94989
Identifiers
RefSeq protein ID
NP_079290
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22899
NP_776089
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22899
XP_011522036
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22899
XP_011522037
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22899
XP_011522038
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22899
XP_011522039
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22899
UniProt protein ID
O94989
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O94989
Ensembl protein ID
ENSP00000355026
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000355026
ENSP00000412505
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412505
ENSP00000462796
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000462796
ENSP00000463875
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000463875
ENSP00000464540
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000464540
ENSP00000498197
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000498197
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