(Q21101948)

Dbl homology (DH) domain superfamily

1 reference

CH domain superfamily

1 reference

PH-like domain superfamily

1 reference

pleckstrin homology domain, protein family

1 reference

Calponin homology domain, protein family

1 reference

Rho guanine nucleotide exchange factor 7, SH3 domain, protein family

1 reference

Dbl homology (DH) domain, protein family

1 reference

SH3 domain, protein family

1 reference

Guanine-nucleotide dissociation stimulator, CDC24, conserved site, protein family

1 reference

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

1 reference

13 November 2019

1 reference

13 November 2019

24 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

betaPIX controls cell motility and neurite extension by regulating the distribution of GIT1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Nox1 activation by βPix and the role of Ser-340 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

A human MAP kinase interactome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

guanyl-nucleotide exchange factor activity

IPI

7 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Synapse formation is regulated by the signaling adaptor GIT1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

regulation of GTP binding

1 reference

31 October 2017

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

intracellular signal transduction

IMP

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

negative regulation of epidermal growth factor receptor signaling pathway

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

positive regulation of lamellipodium morphogenesis

1 reference

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

ephrin receptor signaling pathway

IMP

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

nervous system development

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

focal adhesion assembly

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

positive regulation of substrate adhesion-dependent cell spreading

IDA

1 reference

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

positive regulation of growth hormone secretion

IMP

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

hematopoietic progenitor cell differentiation

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

positive regulation of protein binding

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

regulation of Rho protein signal transduction

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

regulation of small GTPase mediated signal transduction

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

positive regulation of fibroblast migration

1 reference

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

1 reference

31 October 2017

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

positive regulation of GTPase activity

3 references

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

31 October 2017

ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

G protein-coupled receptor signaling pathway

IDA

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14155&geneProductId=UniProtKB:Q14155

has part(s)

Dbl homology (DH) domain

1 reference

SH3 domain

1 reference

pleckstrin homology domain

1 reference

Guanine-nucleotide dissociation stimulator, CDC24, conserved site

1 reference

Calponin homology domain

1 reference

Rho guanine nucleotide exchange factor 7, SH3 domain

1 reference