(Q21102059)

English

Coronin 1B

mammalian protein found in Homo sapiens

coronin-1B
Coronin-2
coronin, actin binding protein, 1B
CORO1B

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BR76

WD40-repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BR76

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BR76

Domain of unknown function DUF1899, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

Arp2/3 complex binding

determination method

3 references

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

protein binding

determination method

4 references

9 May 2019

Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Isoform diversity in the Arp2/3 complex determines actin filament dynamics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

identical protein binding

determination method

1 reference

9 May 2019

Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

cadherin binding

determination method

1 reference

17 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BR76&geneProductId=UniProtKB:Q9BR76

determination method

cadherin binding

determination method

1 reference

9 May 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

actin filament binding

determination method

3 references

9 May 2019

Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

F-actin binding is essential for coronin 1B function in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

9 May 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BR76&geneProductId=UniProtKB:Q9BR76

determination method

plasma membrane

determination method

1 reference

9 May 2019

Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

9 May 2019

Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

perinuclear region of cytoplasm

determination method

1 reference

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

extracellular exosome

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

9 May 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

biological process

positive regulation of lamellipodium morphogenesis

determination method

1 reference

9 May 2019

Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

ruffle organization

determination method

1 reference

9 May 2019

Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

determination method

1 reference

9 May 2019

Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

actin filament branching

determination method

1 reference

9 May 2019

Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

cellular response to platelet-derived growth factor stimulus

determination method

1 reference

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

regulation of Arp2/3 complex-mediated actin nucleation

determination method

1 reference

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

negative regulation of Arp2/3 complex-mediated actin nucleation

determination method

actin filament bundle assembly

determination method

1 reference

9 May 2019

F-actin binding is essential for coronin 1B function in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

protein localization to cell leading edge

determination method

1 reference

9 May 2019

Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

negative regulation of smooth muscle cell chemotaxis

determination method

1 reference

9 May 2019

Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

endothelial cell chemotaxis

determination method

determination method

1 reference

8 April 2019

Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

actin cytoskeleton organization

determination method

1 reference

9 May 2019

Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

actin filament organization

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BR76

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BR76

Domain of unknown function DUF1899

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BR76

WD40 repeat, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BR76

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000340211

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000340211

ENSP00000377471

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377471

ENSP00000438056

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000438056

ENSP00000445330

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000445330

ENSP00000479949

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000479949

ENSP00000486585

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486585

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Multilingual sites(0 entries)

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