Wikidata

(Q21102511)

English

Platelet derived growth factor receptor alpha

mammalian protein found in Homo sapiens

  • CD140a antigen
  • Alpha platelet-derived growth factor receptor
  • PDGFRA
  • platelet-derived growth factor receptor, alpha polypeptide
  • CD140 antigen-like family member A
  • platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor alpha receptor
  • PDGFR-2
  • alpha-type platelet-derived growth factor receptor
  • PDGF-R-alpha
  • platelet-derived growth factor receptor 2
In more languages
default for all languages
No label defined

No description defined

Statements

part of
molecular function
protein binding
determination method or standard
IPI
8 references
retrieved
8 April 2019
stated in
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
Differential interaction of CrkII adaptor protein with platelet-derived growth factor alpha- and beta-receptors is determined by its internal tyrosine phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
platelet-derived growth factor alpha-receptor activity
determination method or standard
IDA
IEA
IMP
6 references
retrieved
31 October 2017
stated in
Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IMP
retrieved
31 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IEA
retrieved
31 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IEA
retrieved
31 October 2017
stated in
Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
31 October 2017
stated in
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
31 October 2017
stated in
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IDA
platelet-derived growth factor binding
determination method or standard
IDA
IEA
IPI
5 references
retrieved
31 October 2017
stated in
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
31 October 2017
stated in
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
31 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IEA
retrieved
31 October 2017
stated in
Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
31 October 2017
stated in
Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
determination method or standard
IDA
platelet-derived growth factor alpha-receptor activity
determination method or standard
IBA
IDA
IEA
IMP
7 references
retrieved
8 April 2019
stated in
Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IEA
retrieved
8 April 2019
stated in
Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
8 April 2019
stated in
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
8 April 2019
stated in
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IBA
platelet-derived growth factor binding
determination method or standard
IBA
IDA
IEA
IPI
6 references
retrieved
8 April 2019
stated in
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IPI
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IEA
retrieved
8 April 2019
stated in
Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
8 April 2019
stated in
Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
GOA
curator
UniProt
UniProt protein ID
P16234
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
determination method or standard
IBA
cell component
biological process

Identifiers

 
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