(Q21103118)

English

Rap1 GTPase-GDP dissociation stimulator 1

mammalian protein found in Homo sapiens

exchange factor smgGDS
SMG P21 stimulatory GDP/GTP exchange protein
SMG GDS protein
rap1 GTPase-GDP dissociation stimulator 1
RAP1GDS1
RAP1, GTP-GDP dissociation stimulator 1

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Statements

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

IPI

GTPase activator activity

3 references

8 April 2019

Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

1 reference

26 September 2017

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52306&geneProductId=UniProtKB:P52306

determination method

IDA

extracellular exosome

1 reference

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52306&geneProductId=UniProtKB:P52306

determination method

IDA

endoplasmic reticulum

1 reference

8 April 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

1 reference

8 April 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

IDA

extracellular exosome

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

HDA

biological process

negative regulation of endoplasmic reticulum calcium ion concentration

1 reference

8 April 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

IMP

positive regulation of mitochondrial calcium ion concentration

1 reference

8 April 2019

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

IMP

vascular associated smooth muscle contraction

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

IEA

myosin filament assembly

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52306

determination method

IEA

small GTPase mediated signal transduction

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52306&geneProductId=UniProtKB:P52306

determination method

IBA

positive regulation of GTPase activity

determination method

IBA

IEA

physically interacts with

1 reference

https://thebiogrid.org/news/227

retrieved

19 April 2020

stated in

BioGRID

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Identifiers

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

13 November 2019

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(Q21103118)

Rap1 GTPase-GDP dissociation stimulator 1

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