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(Q21103288)
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English
GRB2 related adaptor protein
mammalian protein found in Homo sapiens
GRAP
growth factor receptor-bound protein 2-related adaptor protein
GRB2-related adapter protein
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13588
part of
SH3-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13588
SH2 domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13588
SH2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
GRAP, N-terminal SH3 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SH3 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13588
encoded by
GRAP
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13588
molecular function
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13588
determination method
IPI
non-membrane spanning protein tyrosine kinase activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
signaling receptor binding
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
cell component
cytoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13588
determination method
TAS
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13588
determination method
TAS
extrinsic component of cytoplasmic side of plasma membrane
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
biological process
cell-cell signaling
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13588
determination method
TAS
Ras protein signal transduction
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13588
determination method
TAS
positive regulation of signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13588
determination method
IEA
transmembrane receptor protein tyrosine kinase signaling pathway
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
cell migration
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
cell differentiation
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
peptidyl-tyrosine autophosphorylation
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
regulation of cell population proliferation
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
innate immune response
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13588&geneProductId=UniProtKB:Q13588
determination method
IBA
has part(s)
SH2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13588
SH3 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13588
GRAP, N-terminal SH3 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13588
Identifiers
RefSeq protein ID
NP_001317077
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
10750
NP_006604
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
10750
UniProt protein ID
Q13588
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13588
Ensembl protein ID
ENSP00000284154
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000284154
ENSP00000378997
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000378997
ENSP00000459833
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000459833
ENSP00000464328
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000464328
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