(Q21103298)

English

GSK3B interacting protein

mammalian protein found in Homo sapiens

GSKIP
GSK3-beta interaction protein
GSK3B-interacting protein

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Statements

1 reference

13 November 2019

GSK3B-interacting protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9P0R6

GSKIP domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9P0R6

GSKIP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

8 April 2019

The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

8 April 2019

GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IPI

protein kinase inhibitor activity

1 reference

5 June 2018

GSKIP, an inhibitor of GSK3beta, mediates the N-cadherin/beta-catenin pool in the differentiation of SH-SY5Y cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P0R6&geneProductId=UniProtKB:Q9P0R6

1 reference

8 April 2019

The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IDA

protein kinase A regulatory subunit binding

1 reference

8 April 2019

The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IPI

protein kinase A binding

3 references

8 April 2019

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

8 April 2019

GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IEA

protein kinase inhibitor activity

determination method

IDA

IMP

protein kinase binding

1 reference

8 April 2019

GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

8 April 2019

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

8 April 2019

GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IDA

biological process

negative regulation of protein kinase activity

1 reference

5 June 2018

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P0R6&geneProductId=UniProtKB:Q9P0R6

determination method

IEA

intrinsic apoptotic signaling pathway in response to oxidative stress

1 reference

8 April 2019

GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IMP

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IDA

regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IEA

negative regulation of protein kinase activity

1 reference

8 April 2019

GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

determination method

IMP

regulation of Wnt signaling pathway

1 reference

8 April 2019

GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0R6

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9P0R6

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

22 March 2016

language of work or name

English

(Q21103298)

GSK3B interacting protein

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