(Q21104681)

http://www.ebi.ac.uk/interpro/protein/P45379

Troponin domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P45379

1 reference

13 November 2019

1 reference

13 November 2019

protein-macromolecule adaptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

8 April 2019

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

24 April 2018

Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

3 references

8 April 2019

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

calcium-dependent ATPase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

3 references

8 April 2019

Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

24 April 2018

Ca2+, pH and the regulation of cardiac myofilament force and ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

24 April 2018

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

24 April 2018

Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

1 reference

8 April 2019

Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

striated muscle thin filament

TAS

1 reference

8 April 2019

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

8 April 2019

A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis

cardiac Troponin complex

1 reference

8 April 2019

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379

regulation of heart contraction

1 reference

8 April 2019

Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

positive regulation of ATP-dependent activity

2 references

8 April 2019

Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

negative regulation of ATP-dependent activity

1 reference

8 April 2019

Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

response to calcium ion

ventricular cardiac muscle tissue morphogenesis

1 reference

8 April 2019

Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

actin crosslink formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

muscle filament sliding

3 references

8 April 2019

8 April 2019

Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

regulation of muscle filament sliding speed

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

protein heterooligomerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

skeletal muscle contraction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

sarcomere organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

response to calcium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

cardiac muscle contraction

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379