(Q21104745)

C2 domain superfamily

1 reference

SH2 domain superfamily

1 reference

Ras GTPase-activating protein 1

1 reference

Rho GTPase activation protein

1 reference

PH-like domain superfamily

1 reference

pleckstrin homology domain, protein family

1 reference

RasGAP, SH3 domain, protein family

1 reference

SH2 domain, protein family

1 reference

Ras GTPase-activating protein 1, C-terminal SH2 domain, protein family

1 reference

C2 domain, protein family

1 reference

Ras GTPase-activating domain, protein family

1 reference

Ras GTPase-activating protein 1, N-terminal SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Ras GTPase-activating protein, conserved site, protein family

1 reference

potassium channel inhibitor activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

1 January 2018

GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

19 references

1 January 2018

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

A Ras-GTPase-activating protein SH3-domain-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Charting the molecular links between driver and susceptibility genes in colorectal cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

A quantitative protein interaction network for the ErbB receptors using protein microarrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Tyrosine phosphorylation of caveolin-2 at residue 27: differences in the spatial and temporal behavior of phospho-Cav-2 (pY19 and pY27).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

1 January 2018

Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

GTPase activator activity

IPI

5 references

27 February 2018

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

27 February 2018

Regulation of the Ras signaling pathway by GTPase-activating protein in PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

phosphotyrosine residue binding

EXP

1 reference

1 January 2018

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

GTPase activator activity

4 references

1 January 2018

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 January 2018

Regulation of the Ras signaling pathway by GTPase-activating protein in PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

3 references

27 February 2018

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

intrinsic component of the cytoplasmic side of the plasma membrane

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20936&geneProductId=UniProtKB:P20936

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

negative regulation of neuron apoptotic process

IEA

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

negative regulation of cell adhesion

ISS

1 reference

1 January 2018

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

intracellular signal transduction

IDA

1 reference

1 January 2018

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

blood vessel morphogenesis

NAS

1 reference

1 January 2018

A novel RASA1 mutation causing capillary malformation-arteriovenous malformation (CM-AVM) presenting during pregnancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

ephrin receptor signaling pathway

IMP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

regulation of GTPase activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

negative regulation of cell-matrix adhesion

1 reference

1 January 2018

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

regulation of actin filament polymerization

ISS

1 reference

1 January 2018

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

positive regulation of GTPase activity

IDA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

regulation of RNA metabolic process

IEA

1 reference

1 January 2018

Ras-GTPase activating protein (GAP): a putative effector for Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

Ras-GTPase activating protein (GAP): a putative effector for Ras

NAS

regulation of cell shape

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

negative regulation of apoptotic process

NAS

1 reference

1 January 2018

Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

negative regulation of Ras protein signal transduction

IDA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20936

1 reference

pleckstrin homology domain

1 reference

SH2 domain

1 reference

Ras GTPase-activating protein, conserved site

1 reference

Ras GTPase-activating domain

1 reference

C2 domain

1 reference

RasGAP, SH3 domain

1 reference

Ras GTPase-activating protein 1, N-terminal SH2 domain

1 reference

Ras GTPase-activating protein 1, C-terminal SH2 domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016