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(Q21104821)
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SH2 domain containing adaptor protein B
mammalian protein found in Homo sapiens
SHB adaptor protein (a Src homology 2 protein)
SHB (Src homology 2 domain containing) adaptor protein B
Src homology 2 domain containing adaptor protein B
SH2 domain-containing adapter protein B
SHB
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15464
part of
SH2 domain-containing adapter protein B
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15464
SH2 domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15464
SHB, SH2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SH2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15464
encoded by
SHB
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15464
molecular function
phosphotyrosine residue binding
determination method
IPI
1 reference
retrieved
16 July 2018
stated in
Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15464&geneProductId=UniProtKB:Q15464
determination method
IPI
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IPI
retrieved
8 April 2019
stated in
Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IPI
phosphotyrosine residue binding
determination method
IBA
IPI
2 references
retrieved
8 April 2019
stated in
Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IBA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
nucleoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IDA
cytosol
determination method
IDA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IDA
cytoplasmic ribonucleoprotein granule
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IDA
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
vascular endothelial growth factor receptor signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
TAS
angiogenesis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15464
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
positive regulation of signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
signal transduction
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Shb is a ubiquitously expressed Src homology 2 protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15464
determination method
IEA
has part(s)
SH2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15464
SHB, SH2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15464
Identifiers
RefSeq protein ID
NP_003019
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6461
UniProt protein ID
Q15464
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15464
Ensembl protein ID
ENSP00000366936
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000366936
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