(Q21105081)

English

Aminoacyl tRNA synthetase complex interacting multifunctional protein 1

mammalian protein found in Homo sapiens

AIMP1
ARS-interacting multifunctional protein 1
multisynthetase complex auxiliary component p43
endothelial monocyte-activating polypeptide 2
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
endothelial-monocyte activating polypeptide II
aminoacyl tRNA synthase complex-interacting multifunctional protein 1
multisynthase complex auxiliary component p43

In more languages

default for all languages

No label defined

No description defined

Statements

1 reference

5 December 2018

UniProt protein ID

Nucleic acid-binding, OB-fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12904

tRNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

5 December 2018

UniProt protein ID

1 reference

5 December 2018

UniProt protein ID

molecular function

protein homodimerization activity

determination method or standard

1 reference

8 April 2019

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

protein binding

determination method or standard

4 references

8 April 2019

Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Global landscape of HIV-human protein complexes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

4 references

17 October 2017

The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

cytokine activity

determination method or standard

4 references

8 April 2019

A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory res

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

5 references

8 April 2019

The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

Golgi apparatus

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

17 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

aminoacyl-tRNA synthetase multienzyme complex

determination method or standard

3 references

17 October 2017

Dissection of the structural organization of the aminoacyl-tRNA synthetase complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

Isolation and characterization of human nuclear and cytosolic multisynthetase complexes and the intracellular distribution of p43/EMAPII

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

transport vesicle

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

extracellular region

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

methionyl glutamyl tRNA synthetase complex

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

extracellular space

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

extracellular space

determination method or standard

3 references

8 April 2019

A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory res

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

aminoacyl-tRNA synthetase multienzyme complex

determination method or standard

4 references

8 April 2019

Dissection of the structural organization of the aminoacyl-tRNA synthetase complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Isolation and characterization of human nuclear and cytosolic multisynthetase complexes and the intracellular distribution of p43/EMAPII

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

biological process

blood vessel morphogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

protein biosynthesis

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

cell-cell signaling

determination method or standard

1 reference

8 April 2019

Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

negative regulation of endothelial cell proliferation

determination method or standard

1 reference

8 April 2019

Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory res

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

defense response to virus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

response to wounding

determination method or standard

1 reference

8 April 2019

A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory res

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

glucose metabolic process

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

leukocyte migration

determination method or standard

1 reference

8 April 2019

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

signal transduction

determination method or standard

1 reference

8 April 2019

The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

tRNA aminoacylation for protein translation

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

inflammatory response

determination method or standard

3 references

17 October 2017

A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory res

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

carbohydrate metabolic process

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12904&geneProductId=UniProtKB:Q12904

determination method or standard

regulation of signaling receptor activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

inflammatory response

determination method or standard

positive regulation of glucagon secretion

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12904

determination method or standard

tRNA-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12904

Identifiers

RefSeq protein ID

1 reference

7 December 2018

1 reference

7 December 2018

1 reference

7 December 2018

1 reference

7 December 2018

1 reference

7 December 2018

UniProt protein ID

1 reference

5 December 2018

UniProt protein ID

Ensembl protein ID

ENSP00000350699

1 reference

ensembl Release 96

Ensembl protein ID

ENSP00000350699

ENSP00000378191

1 reference

ensembl Release 96

Ensembl protein ID

ENSP00000378191

ENSP00000405248

1 reference

ensembl Release 96

Ensembl protein ID

ENSP00000405248

ENSP00000423681

1 reference

ensembl Release 96

Ensembl protein ID

ENSP00000423681

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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