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English
ADAM metallopeptidase with thrombospondin type 1 motif 8
mammalian protein found in Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 8
METH-8
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
ADAMTS8
ADAMTS-8
METH-2
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UP79
part of
Thrombospondin type-1 (TSP1) repeat superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
Metallopeptidase, catalytic domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
Peptidase M12B, ADAM-TS8
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
Peptidase M12B, ADAM/reprolysin, protein family
1 reference
based on heuristic
inferred from protein domain or family
ADAM-TS Spacer 1, protein family
1 reference
based on heuristic
inferred from protein domain or family
ADAM, cysteine-rich, protein family
1 reference
based on heuristic
inferred from protein domain or family
Thrombospondin type-1 (TSP1) repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
Peptidase M12B, propeptide family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UP79
encoded by
ADAMTS8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UP79
molecular function
integrin binding
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
TAS
zinc ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
metalloendopeptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
heparin binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
low-affinity phosphate transmembrane transporter activity
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
ADAM-TS8, a novel metalloprotease of the ADAM-TS family located on mouse chromosome 9 and human chromosome 11
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
TAS
metallopeptidase activity
determination method
TAS
IEA
3 references
retrieved
8 April 2019
stated in
METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
extracellular matrix
determination method
ISS
1 reference
retrieved
24 April 2018
stated in
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP79&geneProductId=UniProtKB:Q9UP79
determination method
ISS
collagen-containing extracellular matrix
determination method
IEA
ISS
2 references
retrieved
8 April 2019
stated in
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
biological process
proteolysis
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UP79
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
negative regulation of cell population proliferation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
TAS
phosphate ion transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP79
determination method
IEA
has part(s)
Thrombospondin type-1 (TSP1) repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
Peptidase M12B, ADAM/reprolysin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
ADAM-TS Spacer 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
ADAM, cysteine-rich
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
Peptidase M12B, propeptide
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UP79
Identifiers
RefSeq protein ID
NP_008968
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11095
XP_016872634
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11095
UniProt protein ID
Q9UP79
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UP79
Ensembl protein ID
ENSP00000257359
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000257359
Transporter Classification Database ID
8.A.77.1
1 reference
based on heuristic
TCDB BLAST
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