(Q21105609)

English

Cystatin F

mammalian protein found in Homo sapiens

cystatin-like metastasis-associated protein
CMAP
cystatin-F
leukocystatin
cystatin-7
CST7

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O76096

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptidase inhibitor activity

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

endopeptidase inhibitor activity

determination method

1 reference

8 April 2019

Leukocystatin, a new Class II cystatin expressed selectively by hematopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

protein binding

determination method

1 reference

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

protease binding

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

cysteine-type endopeptidase inhibitor activity

determination method

4 references

27 March 2018

Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

cysteine-type endopeptidase inhibitor activity

determination method

4 references

8 April 2019

Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

peptidase inhibitor activity

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

protein homodimerization activity

determination method

3 references

8 April 2019

Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

extracellular region

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

extracellular space

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

extracellular space

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

extracellular space

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Regulated expression and intracellular localization of cystatin F in human U937 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

determination method

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

determination method

1 reference

8 April 2019

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

multivesicular body

determination method

1 reference

8 April 2019

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

endoplasmic reticulum

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

Golgi apparatus

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

cytoplasmic vesicle

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Regulated expression and intracellular localization of cystatin F in human U937 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

biological process

negative regulation of peptidase activity

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

immune response

determination method

1 reference

8 April 2019

Leukocystatin, a new Class II cystatin expressed selectively by hematopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

negative regulation of cysteine-type endopeptidase activity

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

negative regulation of endopeptidase activity

determination method

1 reference

14 January 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76096&geneProductId=UniProtKB:O76096

determination method

positive regulation of myelination

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

inhibition of cysteine-type endopeptidase activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

negative regulation of microglial cell activation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

negative regulation of peptidase activity

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

8 April 2019

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76096

determination method

Cystatin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O76096

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000420384

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420384

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

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Multilingual sites(0 entries)

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