(Q21105620)

Papain-like cysteine peptidase superfamily

1 reference

Peptidase C19, ubiquitin carboxyl-terminal hydrolase family

1 reference

USP8 dimerisation domain, protein family

1 reference

Ubiquitin specific protease domain, protein family

1 reference

Rhodanese-like domain, protein family

1 reference

Ubiquitin specific protease, conserved site, protein family

1 reference

cysteine-type peptidase activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

5 references

8 April 2019

Final stages of cytokinesis and midbody ring formation are controlled by BRUCE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Ab initio protein modelling reveals novel human MIT domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

thiol-dependent deubiquitinase

IPI

4 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

27 February 2018

UBPY: a growth-regulated human ubiquitin isopeptidase.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

27 February 2018

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

27 February 2018

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

cysteine-type endopeptidase activity

IDA

1 reference

8 April 2019

Deubiquitinating enzymes: a new class of biological regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

27 February 2018

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

thiol-dependent deubiquitinase

IDA

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

UBPY: a growth-regulated human ubiquitin isopeptidase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

extrinsic component of endosome membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

27 February 2018

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

extrinsic component of plasma membrane

1 reference

27 February 2018

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

27 February 2018

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

protein K48-linked deubiquitination

biological process

1 reference

27 February 2018

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

ubiquitin-dependent protein catabolic process

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

1 reference

8 April 2019

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

endosome organization

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

protein K63-linked deubiquitination

1 reference

27 February 2018

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

cell population proliferation

1 reference

1 January 2018

UBPY: a growth-regulated human ubiquitin isopeptidase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

TAS

protein deubiquitination

3 references

27 February 2018

27 February 2018

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

cellular response to dexamethasone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

cellular response to nerve growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

Ras protein signal transduction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation

protein deubiquitination

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 January 2018

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818

regulation of protein stability

1 reference

8 April 2019

The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

regulation of protein localization

1 reference

8 April 2019

The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

regulation of protein catabolic process at postsynapse, modulating synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

protein deubiquitination

5 references

8 April 2019

8 April 2019

The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818

Peptidase C19, ubiquitin carboxyl-terminal hydrolase

has part(s)

1 reference

Ubiquitin specific protease, conserved site

1 reference

USP8 dimerisation domain

1 reference

Rhodanese-like domain

1 reference

Ubiquitin specific protease domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016