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(Q21105749)
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English
D-2-hydroxyglutarate dehydrogenase
mammalian protein found in Homo sapiens
D-2-hydroxyglutarate dehydrogenase, mitochondrial
D2HGDH
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N465
part of
Vanillyl-alcohol oxidase, C-terminal subdomain 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD-binding, type PCMH-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD-linked oxidase-like, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD-binding, type PCMH, subdomain 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD-binding, type PCMH, subdomain 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD-oxidase
1 reference
based on heuristic
inferred from protein domain or family
FAD-linked oxidase, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
FAD-binding domain, PCMH-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N465
encoded by
D2HGDH
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N465
molecular function
oxidoreductase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N465
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
catalytic activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
flavin adenine dinucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
oxidoreductase activity, acting on CH-OH group of donors
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N465&geneProductId=UniProtKB:Q8N465
determination method
IEA
D-lactate dehydrogenase (cytochrome) activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
(R)-2-hydroxyglutarate dehydrogenase activity
determination method
EXP
IBA
IEA
ISS
4 references
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
EXP
FAD binding
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N465&geneProductId=UniProtKB:Q8N465
determination method
IBA
FAD binding
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
cell component
mitochondrial matrix
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
TAS
mitochondrion
determination method
IBA
IEA
ISS
4 references
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N465
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
extrinsic component of cytoplasmic side of plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
biological process
response to calcium ion
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
response to zinc ion
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
response to magnesium ion
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
response to cobalt ion
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
response to manganese ion
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
Identification of a dehydrogenase acting on D-2-hydroxyglutarate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IEA
2-oxoglutarate metabolic process
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
TAS
lactate oxidation
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
respiratory electron transport chain
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N465
determination method
IBA
has part(s)
FAD-linked oxidase, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD-binding domain, PCMH-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
FAD linked oxidase, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N465
Identifiers
RefSeq protein ID
NP_001274178
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
NP_689996
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510036
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510037
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510038
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510039
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510040
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510041
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510042
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510043
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510045
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510046
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510047
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510048
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510049
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510051
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510052
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510053
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510054
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510055
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510058
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510059
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510060
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510061
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_011510062
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_016860316
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_016860317
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_016860318
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_016860319
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_016860321
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
NP_001339753
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_024308870
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
XP_024308871
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
728294
UniProt protein ID
Q8N465
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N465
Ensembl protein ID
ENSP00000315351
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000315351
ENSP00000383580
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000383580
ENSP00000384723
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000384723
ENSP00000392602
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000392602
ENSP00000395837
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000395837
ENSP00000400212
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000400212
ENSP00000404596
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000404596
ENSP00000412511
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412511
Sitelinks
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(0 entries)
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Wikibooks
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Wikinews
(0 entries)
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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