Wikidata

(Q21106376)

English

Transcription factor AP-2 alpha

mammalian protein found in Homo sapiens

  • activator protein 2
  • AP-2
  • activating enhancer-binding protein 2-alpha
  • TFAP2A
  • AP2-alpha
  • transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
  • AP-2 transcription factor
  • transcription factor AP-2-alpha
In more languages

Statements

molecular function
DNA-binding transcription repressor activity, RNA polymerase II-specific
determination method
IDA
6 references
retrieved
10 September 2018
stated in
A family of AP-2 proteins down-regulate manganese superoxide dismutase expression
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
10 September 2018
stated in
Derepression of the C/EBPalpha gene during adipogenesis: identification of AP-2alpha as a repressor
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
10 September 2018
stated in
AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
A family of AP-2 proteins down-regulate manganese superoxide dismutase expression
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
Derepression of the C/EBPalpha gene during adipogenesis: identification of AP-2alpha as a repressor
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
protein binding
determination method
IPI
12 references
retrieved
8 April 2019
stated in
Tau promoter confers neuronal specificity and binds Sp1 and AP-2
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
retrieved
8 April 2019
stated in
Sumoylation pathway is required to maintain the basal breast cancer subtype
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IPI
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IBA
IDA
ISA
ISM
NAS
6 references
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
NAS
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
ISM
retrieved
8 April 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
ISA
retrieved
8 April 2019
stated in
Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
Cloning and characterization of a second AP-2 transcription factor: AP-2 beta
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IBA
cell component
nucleus
determination method
IBA
IDA
IEA
IMP
6 references
retrieved
8 April 2019
stated in
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IEA
retrieved
8 April 2019
stated in
AP2 transcription factor induces apoptosis in retinoblastoma cells
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation
GOA
curator
UniProt
UniProt protein ID
P05549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549
determination method
IBA
biological process

Identifiers

 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21106376&oldid=2022927897"