(Q21106470)

English

Aquaporin 5

mammalian protein found in Homo sapiens

aquaporin-5
AQP5

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transporter activity

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

protein binding

determination method

3 references

9 May 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

An empirical framework for binary interactome mapping

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

water channel activity

determination method

26 references

17 October 2017

The human Aquaporin-5 gene. Molecular characterization and chromosomal localization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Functional characterization and localization of AQP3 in the human colon

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Aquaporin-1, nothing but a water channel.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Functional impairment of lens aquaporin in two families with dominantly inherited cataracts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Novel variants in human Aquaporin-4 reduce cellular water permeability

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Mechanism of selectivity in aquaporins and aquaglyceroporins.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Water permeability and characterization of aquaporin-11.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Mercury-sensitive residues and pore site in AQP3 water channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Structural determinants of water permeation through aquaporin-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Functional and molecular characterization of the human neutral solute channel aquaporin-9.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Identification of arylsulfonamides as Aquaporin 4 inhibitors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Purification and functional characterization of aquaporin-8.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Functional characterization of a human aquaporin 0 mutation that leads to a congenital dominant lens cataract

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

identical protein binding

determination method

1 reference

9 May 2019

High-resolution x-ray structure of human aquaporin 5

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

water channel activity

determination method

27 references

1 January 2018

The human Aquaporin-5 gene. Molecular characterization and chromosomal localization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Functional characterization and localization of AQP3 in the human colon

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Aquaporin-1, nothing but a water channel.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Functional impairment of lens aquaporin in two families with dominantly inherited cataracts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Structural determinants of water permeation through aquaporin-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Purification and functional characterization of aquaporin-8.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Mercury-sensitive residues and pore site in AQP3 water channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Novel variants in human Aquaporin-4 reduce cellular water permeability

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Water permeability and characterization of aquaporin-11.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Functional characterization of a human aquaporin 0 mutation that leads to a congenital dominant lens cataract

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Identification of arylsulfonamides as Aquaporin 4 inhibitors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Functional and molecular characterization of the human neutral solute channel aquaporin-9.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Mechanism of selectivity in aquaporins and aquaglyceroporins.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

1 January 2018

Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

channel activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

water channel activity

determination method

3 references

1 January 2018

The human Aquaporin-5 gene. Molecular characterization and chromosomal localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

1 January 2018

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

water channel activity

determination method

3 references

9 May 2019

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

High-resolution x-ray structure of human aquaporin 5

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

integral component of membrane

determination method

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

plasma membrane

determination method

integral component of plasma membrane

determination method

1 reference

1 January 2018

The human Aquaporin-5 gene. Molecular characterization and chromosomal localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

basal plasma membrane

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

apical plasma membrane

determination method

3 references

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

17 October 2017

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

endoplasmic reticulum

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

extracellular exosome

determination method

1 reference

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

plasma membrane

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

apical plasma membrane

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

extracellular exosome

determination method

1 reference

9 May 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

integral component of plasma membrane

determination method

1 reference

9 May 2019

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

cytoplasmic vesicle membrane

determination method

1 reference

8 April 2019

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

cytoplasmic vesicle

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

biological process

determination method

1 reference

1 January 2018

The human Aquaporin-5 gene. Molecular characterization and chromosomal localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

water transport

determination method

pancreatic juice secretion

determination method

1 reference

9 May 2019

Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

saliva secretion

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

determination method

1 reference

9 May 2019

Aquaporin expression in developing human teeth and selected orofacial tissues

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

ion transmembrane transport

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55064&geneProductId=UniProtKB:P55064

determination method

camera-type eye morphogenesis

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

carbon dioxide transport

determination method

3 references

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

transmembrane transport

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

water transport

determination method

cellular hypotonic response

determination method

1 reference

9 May 2019

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55064

determination method

Major intrinsic protein, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P55064

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000293599

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000293599

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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