(Q21106672)

synaptosomal vesicle fusion pore

1 reference

Transporter Classification Database ID

1.F.1.1.1

retrieved

2 October 2019

hierarchical database ID heuristic

Syntaxin, N-terminal domain, protein family

1 reference

inferred from protein domain or family

Target SNARE coiled-coil homology domain, protein family

1 reference

inferred from protein domain or family

Syntaxin/epimorphin, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

9 references

1 January 2018

Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

sphingomyelin phosphodiesterase activator activity

IPI

1 reference

1 January 2018

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

5 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

26 September 2017

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

26 September 2017

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

myelin sheath adaxonal region

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

intracellular anatomical structure

1 reference

1 January 2018

Syntaxin-4 is essential for IgE secretion by plasma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

somatodendritic compartment

1 reference

1 January 2018

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

perinuclear region of cytoplasm

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

extracellular exosome

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

26 September 2017

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

26 September 2017

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

The impact of extracellular syntaxin4 on HaCaT keratinocyte behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

phagocytic vesicle membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

7 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

presynaptic active zone membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

extracellular exosome

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of eosinophil degranulation

HDA

biological process

1 reference

1 January 2018

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of cell migration

1 reference

1 January 2018

Involvement of syntaxin 4 in the transport of membrane-type 1 matrix metalloproteinase to the plasma membrane in human gastric epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

synaptic vesicle fusion to presynaptic active zone membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

response to hydroperoxide

1 reference

1 January 2018

The impact of extracellular syntaxin4 on HaCaT keratinocyte behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of catalytic activity

1 reference

1 January 2018

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

post-Golgi vesicle-mediated transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

TAS

regulation of exocytosis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of protein localization to plasma membrane

3 references

1 January 2018

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 January 2018

Involvement of syntaxin 4 in the transport of membrane-type 1 matrix metalloproteinase to the plasma membrane in human gastric epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of chemotaxis

1 reference

1 January 2018

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of cell population proliferation

1 reference

1 January 2018

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of protein localization to cell surface

1 reference

1 January 2018

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

regulation of extrinsic apoptotic signaling pathway via death domain receptors

1 reference

1 January 2018

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of insulin secretion involved in cellular response to glucose stimulus

neurotransmitter transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

vesicle-mediated transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

SNARE complex assembly

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

positive regulation of cell adhesion

1 reference

1 January 2018

Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

long-term potentiation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

cytokine-mediated signaling pathway

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

cellular response to interferon-gamma

TAS

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846

Target SNARE coiled-coil homology domain

has part(s)

1 reference

Syntaxin, N-terminal domain

1 reference

Syntaxin/epimorphin, conserved site

1 reference

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1.F.1.1.1

2 references

Transporter Classification database

retrieved

13 March 2020