(Q21107313)

http://www.ebi.ac.uk/interpro/protein/Q99623

Band 7/SPFH domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99623

Band 7 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein N-terminus binding

1 reference

8 April 2019

PHB2 interacts with RNF2 and represses CP2c-stimulated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 reference

8 April 2019

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

protein C-terminus binding

IPI

1 reference

8 April 2019

Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 references

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Stomatin-like protein 2 binds cardiolipin and regulates mitochondrial biogenesis and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

estrogen receptor binding

IPI

1 reference

8 April 2019

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

2 references

1 reference

8 April 2019

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

mitochondrial outer membrane

1 reference

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

5 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

extracellular exosome

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

6 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

26 September 2017

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

1 reference

8 April 2019

Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

mitochondrial inner membrane

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

protein-containing complex

1 reference

8 April 2019

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

presynaptic active zone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

mitochondrial inner membrane

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

8 April 2019

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

regulation of transcription, DNA-templated

biological process

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

mammary gland branching involved in thelarche

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

protein stabilization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

regulation of branching involved in mammary gland duct morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

mitochondrion organization

1 reference

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

negative regulation of mammary gland epithelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

PHB2 interacts with RNF2 and represses CP2c-stimulated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

positive regulation of exit from mitosis

1 reference

8 April 2019

ASURA (PHB2) interacts with Scc1 through chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

mammary gland alveolus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

negative regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

PHB2 interacts with RNF2 and represses CP2c-stimulated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99623&geneProductId=UniProtKB:Q99623

sister chromatid cohesion

1 reference

8 April 2019

ASURA (PHB2) interacts with Scc1 through chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

positive regulation of cell cycle G1/S phase transition

1 reference

8 April 2019

ASURA (PHB2) interacts with Scc1 through chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Expression of prohibitins on the surface of activated T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

negative regulation of intracellular estrogen receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

regulation of complement activation

1 reference

8 April 2019

Prohibitin binds to C3 and enhances complement activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

mitochondrial calcium ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

cellular response to retinoic acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

cellular response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99623

1 reference

InterPro Release 71.0