(Q21108408)

http://www.ebi.ac.uk/interpro/protein/P51790

chloride channel, core

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51790

CBS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

volume-sensitive chloride channel activity

1 reference

8 April 2019

ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

protein homodimerization activity

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

protein heterodimerization activity

IPI

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

chloride channel activity

voltage-gated chloride channel activity

TAS

3 references

8 April 2019

Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

solute:proton antiporter activity

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

early endosome membrane

1 reference

8 April 2019

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

late endosome membrane

1 reference

8 April 2019

1 reference

26 September 2017

Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

26 September 2017

Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

transport vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

26 September 2017

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

1 reference

8 April 2019

Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

external side of plasma membrane

1 reference

8 April 2019

Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

integral component of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

negative regulation of cell volume

1 reference

8 April 2019

ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

endosomal lumen acidification

IMP

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

regulation of anion transmembrane transport

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

1 reference

8 April 2019

The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

chloride transmembrane transport

TAS

1 reference

8 April 2019

Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

regulation of anion transport

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51790&geneProductId=UniProtKB:P51790

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

transmembrane transport

1 reference

8 April 2019

synaptic vesicle lumen acidification

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51790

physically interacts with

IBA

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4285

language of work or name

17 August 2016

1 reference

InterPro Release 71.0