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(Q21108425)
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SURF1 cytochrome c oxidase assembly factor
mammalian protein found in Homo sapiens
surfeit 1
surfeit locus protein 1
SURF1
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15526
part of
Surfeit locus 1/Shy1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15526
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15526
encoded by
SURF1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15526
molecular function
cytochrome-c oxidase activity
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly
GOA
curator
UniProt
UniProt protein ID
Q15526
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IPI
retrieved
8 April 2019
stated in
MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IPI
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15526
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
mitochondrial inner membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15526
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
mitochondrion
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15526
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15526
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
mitochondrial respirasome
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
TAS
biological process
proton transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
aerobic respiration
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
TAS
oxidative phosphorylation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IMP
ATP biosynthetic process
determination method
IMP
1 reference
retrieved
5 June 2018
stated in
Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15526&geneProductId=UniProtKB:Q15526
determination method
IMP
respiratory chain complex IV assembly
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
TAS
mitochondrial cytochrome c oxidase assembly
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
SURF1 deficiency causes demyelinating Charcot-Marie-Tooth disease
GOA
curator
UniProt
UniProt protein ID
Q15526
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IMP
electron transport chain
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15526
determination method
IEA
Identifiers
RefSeq protein ID
NP_001267716
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6834
NP_003163
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6834
XP_011517244
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6834
UniProt protein ID
Q15526
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15526
Ensembl protein ID
ENSP00000361042
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000361042
ENSP00000487158
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000487158
ENSP00000486289
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000486289
ENSP00000482067
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000482067
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