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(Q21108716)
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English
H2.0 like homeobox
mammalian protein found in Homo sapiens
homeobox protein HLX1
H2.0-like homeobox protein
HLX
H2.0-like homeo box-1
homeobox protein HB24
H2.0-like homeobox 1
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q14774
part of
Homeobox-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q14774
Homeobox domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
basic helix-loop-helix transcription factor
1 reference
based on heuristic
inferred from protein domain or family
Helix-turn-helix motif, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox domain, metazoa, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q14774
encoded by
HLX
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q14774
molecular function
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IPI
sequence-specific DNA binding
determination method
IEA
IDA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
retrieved
8 April 2019
stated in
Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IDA
DNA binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q14774
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
ISA
ISM
NAS
3 references
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
NAS
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
ISM
retrieved
8 April 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
ISA
cell component
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q14774
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
biological process
negative regulation of T-helper 2 cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
multicellular organism development
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
A human homeobox gene, HB24, inhibits development of CD4+ T cells and impairs thymic involution in transgenic mice
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
TAS
enteric nervous system development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
positive regulation of organ growth
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
positive regulation of cell population proliferation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
skeletal muscle tissue development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q14774
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
liver development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
positive regulation of T-helper 1 cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q14774
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14774&geneProductId=UniProtKB:Q14774
determination method
IEA
embryonic digestive tract morphogenesis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
animal organ development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14774
determination method
IEA
has part(s)
Homeobox domain, metazoa
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q14774
Homeobox domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q14774
Helix-turn-helix motif
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q14774
Homeobox, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q14774
Identifiers
RefSeq protein ID
NP_068777
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3142
UniProt protein ID
Q14774
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q14774
Ensembl protein ID
ENSP00000355870
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000355870
ENSP00000408248
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000408248
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