Wikidata

(Q21108986)

English

Troponin I3, cardiac type

mammalian protein found in Homo sapiens

  • Cardiac troponin I
  • troponin I, cardiac muscle
  • cardiomyopathy, dilated 2A (autosomal recessive)
  • troponin I type 3 (cardiac)
  • TNNI3
In more languages

Statements

molecular function
protein binding
determination method
IPI
12 references
retrieved
8 April 2019
stated in
Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Polycystin-2 interacts with troponin I, an angiogenesis inhibitor
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Troponin I binds polycystin-L and inhibits its calcium-induced channel activation
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Proteins encoded by human Down syndrome critical region gene 1-like 2 (DSCR1L2) mRNA and by a novel DSCR1L2 mRNA isoform interact with cardiac troponin I (TNNI3)
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Proteins encoded by human Down syndrome critical region gene 1-like 2 (DSCR1L2) mRNA and by a novel DSCR1L2 mRNA isoform interact with cardiac troponin I (TNNI3)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IPI
cell component
troponin complex
determination method
IEA
IDA
5 references
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19429&geneProductId=UniProtKB:P19429
determination method
IEA
retrieved
24 April 2018
stated in
Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19429&geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
24 April 2018
stated in
Overexpression of human cardiac troponin-I and troponin-C in Escherichia coli and their purification and characterisation. Two point mutations allow high-level expression of troponin-I
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19429&geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
24 April 2018
stated in
Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19429&geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
24 April 2018
stated in
Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19429&geneProductId=UniProtKB:P19429
determination method
IDA
troponin complex
determination method
IBA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IEA
retrieved
8 April 2019
stated in
Overexpression of human cardiac troponin-I and troponin-C in Escherichia coli and their purification and characterisation. Two point mutations allow high-level expression of troponin-I
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
8 April 2019
stated in
Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
8 April 2019
stated in
Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
8 April 2019
stated in
Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart
GOA
curator
UniProt
UniProt protein ID
P19429
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19429
determination method
IBA
biological process

Identifiers

 
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