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English
Coagulation factor II thrombin receptor like 2
mammalian protein found in Homo sapiens
Coagulation factor II receptor-like 2 (protease-actovated receptor 3)
thrombin receptor-like 2
protease-activated receptor 3
proteinase-activated receptor 3
F2RL2
Coagulation factor II receptor-like 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O00254
part of
Protease-activated receptor 3
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O00254
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O00254
encoded by
F2RL2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O00254
molecular function
thrombin-activated receptor activity
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IPI
retrieved
8 April 2019
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IPI
signal transducer activity
determination method
IEA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00254&geneProductId=UniProtKB:O00254
determination method
IEA
phosphatidylinositol phospholipase C activity
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
G protein-coupled receptor activity
determination method
IBA
IEA
TAS
4 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00254&geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00254&geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00254&geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00254&geneProductId=UniProtKB:O00254
determination method
IBA
G protein-coupled receptor activity
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IBA
cell component
integral component of membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
extracellular region
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
plasma membrane
determination method
TAS
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
8 April 2019
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
integral component of plasma membrane
determination method
TAS
1 reference
retrieved
27 February 2018
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00254&geneProductId=UniProtKB:O00254
determination method
TAS
apical plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
protein-containing complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IDA
integral component of plasma membrane
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IBA
biological process
platelet activation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
hemostasis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
thrombin-activated receptor signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
blood coagulation
determination method
TAS
IEA
3 references
retrieved
8 April 2019
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
response to wounding
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Protease-activated receptor 3 is a second thrombin receptor in humans
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
positive regulation of Rho protein signal transduction
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IBA
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IBA
G protein-coupled receptor signaling pathway
determination method
IEA
TAS
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00254
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00254
determination method
IEA
exact match
https://identifiers.org/uniprot:O00254
1 reference
stated in
Identifiers.org
UniProt protein ID
O00254
reference URL
https://registry.identifiers.org/registry/uniprot
http://purl.uniprot.org/uniprot/O00254
1 reference
stated in
Identifiers.org
UniProt protein ID
O00254
reference URL
https://registry.identifiers.org/registry/uniprot
https://www.ncbi.nlm.nih.gov/protein/O00254
1 reference
stated in
Identifiers.org
UniProt protein ID
O00254
reference URL
https://registry.identifiers.org/registry/uniprot
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O00254
Identifiers
RefSeq protein ID
NP_001243495
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2151
NP_004092
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2151
UniProt protein ID
O00254
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O00254
Ensembl protein ID
ENSP00000296641
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000296641
ENSP00000426703
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426703
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