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Neuroligin 4 Y-linked
mammalian protein found in Homo sapiens
neuroligin-4, Y-linked
alternative HNL4Y
NLGN4Y
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NFZ3
part of
Neuroligin 4
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NFZ3
Alpha/Beta hydrolase fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NFZ3
Carboxylesterase type B
1 reference
based on heuristic
inferred from protein domain or family
Carboxylesterase type B, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NFZ3
encoded by
NLGN4Y
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NFZ3
molecular function
scaffold protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IPI
carboxylic ester hydrolase activity
determination method
IBA
1 reference
retrieved
23 May 2017
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8NFZ3
determination method
IBA
neurexin family protein binding
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IPI
cell adhesion molecule binding
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Neuroligins and neurexins link synaptic function to cognitive disease
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
signaling receptor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
postsynaptic membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
postsynaptic density
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
synapse
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
integral component of plasma membrane
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
cell surface
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
cell junction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
plasma membrane
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
23 May 2017
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8NFZ3
determination method
IEA
spanning component of membrane
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
presynapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
symmetric, GABA-ergic, inhibitory synapse
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
asymmetric, glutamatergic, excitatory synapse
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
biological process
neuron cell-cell adhesion
determination method
TAS
1 reference
retrieved
23 May 2017
stated in
Neuroligins and neurexins link synaptic function to cognitive disease
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8NFZ3
determination method
TAS
synapse organization
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
modulation of chemical synaptic transmission
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
learning
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Analysis of the neuroligin 4Y gene in patients with autism
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IMP
vocalization behavior
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Analysis of the neuroligin 4Y gene in patients with autism
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IMP
cell adhesion
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NFZ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IEA
social behavior
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Analysis of the neuroligin 4Y gene in patients with autism
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IMP
synaptic vesicle endocytosis
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
postsynaptic membrane assembly
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
presynaptic membrane assembly
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
neuron cell-cell adhesion
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Neuroligins and neurexins link synaptic function to cognitive disease
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
IBA
presynapse assembly
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ3
determination method
TAS
has part(s)
carboxylesterase type B, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NFZ3
carboxylesterase, type B
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NFZ3
Identifiers
RefSeq protein ID
NP_001157710
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001193779
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_055708
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_006724937
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_011529729
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_011529730
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_011529731
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_011529732
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_016885525
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_016885528
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_016885529
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_016885530
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
XP_024308258
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352513
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352515
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352517
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352519
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352520
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352521
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
NP_001352522
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22829
UniProt protein ID
Q8NFZ3
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NFZ3
Ensembl protein ID
ENSP00000342535
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000342535
ENSP00000348169
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000348169
ENSP00000372325
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000372325
ENSP00000372320
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000372320
ENSP00000412638
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412638
ENSP00000496594
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000496594
ENSP00000494046
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000494046
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