(Q21109066)

English

Neuroligin 3

mammalian protein found in Homo sapiens

neuroligin-3
gliotactin homolog
NLGN3

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NZ94

Alpha/Beta hydrolase fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NZ94

Carboxylesterase type B

1 reference

based on heuristic

inferred from protein domain or family

Carboxylesterase type B, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

scaffold protein binding

determination method

1 reference

8 April 2019

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

neurexin family protein binding

determination method

3 references

8 April 2019

The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

carboxylic ester hydrolase activity

determination method

1 reference

23 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9NZ94

determination method

cell adhesion molecule binding

determination method

1 reference

8 April 2019

The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

protein binding

determination method

1 reference

8 April 2019

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

2 references

determination method

3 references

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

endocytic vesicle

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

excitatory synapse

determination method

1 reference

8 April 2019

Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

plasma membrane

determination method

2 references

integral component of postsynaptic membrane

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

3 references

8 April 2019

Disorder-associated mutations lead to functional inactivation of neuroligins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

spanning component of membrane

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

symmetric, GABA-ergic, inhibitory synapse

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

asymmetric, glutamatergic, excitatory synapse

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

biological process

regulation of AMPA receptor activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

positive regulation of synaptic vesicle clustering

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

rhythmic synaptic transmission

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

regulation of NMDA receptor activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

regulation of synaptic transmission, glutamatergic

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

excitatory postsynaptic potential

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

synapse organization

determination method

negative regulation of excitatory postsynaptic potential

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

modulation of chemical synaptic transmission

determination method

4 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

1 reference

8 April 2019

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

long-term potentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

vocalization behavior

determination method

1 reference

8 April 2019

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

negative regulation of dendritic spine morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

regulation of dendritic spine morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

receptor-mediated endocytosis

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

oligodendrocyte differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

regulation of terminal button organization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

determination method

1 reference

8 April 2019

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

regulation of long-term synaptic potentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

visual learning

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

synapse assembly

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

synaptic vesicle endocytosis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

postsynaptic membrane assembly

determination method

presynapse assembly

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ94

determination method

carboxylesterase type B, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NZ94

carboxylesterase, type B

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NZ94

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000351591

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000351591

ENSP00000363163

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000363163

ENSP00000445298

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000445298

ENSP00000379196

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000379196

ENSP00000479877

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000479877

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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