(Q21109159)

Serine/threonine kinase 25, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

protein homodimerization activity

1 reference

8 April 2019

YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

14 references

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Structural basis for the unique heterodimeric assembly between cerebral cavernous malformation 3 and germinal center kinase III

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

2 references

protein serine/threonine kinase activity

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

MAP kinase kinase kinase kinase activity

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

intrinsic apoptotic signaling pathway in response to hydrogen peroxide

HDA

biological process

1 reference

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

response to oxidative stress

1 reference

8 April 2019

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

positive regulation of axonogenesis

TAS

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

establishment of Golgi localization

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

establishment or maintenance of cell polarity

IMP

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

protein phosphorylation

IDA

protein autophosphorylation

3 references

1 reference

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

response to hydrogen peroxide

IDA

1 reference

8 April 2019

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

8 April 2019

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

positive regulation of stress-activated MAPK cascade

TAS

1 reference

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

1 reference

17 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

regulation of mitotic cell cycle

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

regulation of apoptotic process

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

neuron projection morphogenesis

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

stress-activated protein kinase signaling cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

activation of protein kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

protein kinase, ATP binding site

has part(s)

1 reference

protein kinase domain

1 reference

Serine/threonine kinase 25, catalytic domain

1 reference