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(Q21109440)
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Ankyrin repeat and LEM domain containing 1
mammalian protein found in Homo sapiens
LEM-domain containing 3
LEM domain containing 6
ankyrin repeat and LEM domain-containing protein 1
ankyrin repeat domain-containing protein 41
LEM-domain containing protein 3
ANKLE1
In more languages
default values for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NAG6
part of
LEM/LEM-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
Ankyrin repeat and LEM domain-containing protein 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
Ankyrin repeat-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
GIY-YIG endonuclease family
1 reference
based on heuristic
inferred from protein domain or family
LEM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ankyrin repeat-containing domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ankyrin repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NAG6
encoded by
ANKLE1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NAG6
molecular function
nuclease activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
endonuclease activity
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IPI
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
chromatin DNA binding
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NAG6&geneProductId=UniProtKB:Q8NAG6
determination method
IBA
cell component
nucleus
determination method
IDA
IEA
IMP
3 references
retrieved
8 April 2019
stated in
Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IDA
integral component of nuclear inner membrane
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NAG6&geneProductId=UniProtKB:Q8NAG6
determination method
IBA
cytoplasm
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
retrieved
8 April 2019
stated in
Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IDA
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IDA
biological process
DNA repair
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
protein export from nucleus
determination method
IDA
IMP
2 references
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IMP
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IDA
cellular response to DNA damage stimulus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IEA
nuclear envelope organization
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NAG6&geneProductId=UniProtKB:Q8NAG6
determination method
IBA
meiotic attachment of telomere to nuclear envelope
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NAG6&geneProductId=UniProtKB:Q8NAG6
determination method
IBA
nucleic acid phosphodiester bond hydrolysis
determination method
IC
1 reference
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IC
positive regulation of response to DNA damage stimulus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
GOA
curator
UniProt
UniProt protein ID
Q8NAG6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NAG6
determination method
IDA
has part(s)
ankyrin repeat-containing domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
LEM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
ankyrin repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
GIY-YIG endonuclease
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NAG6
Identifiers
RefSeq protein ID
NP_001265372
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
126549
NP_001265373
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
126549
NP_001265374
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
126549
NP_689576
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
126549
UniProt protein ID
Q8NAG6
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NAG6
Ensembl protein ID
ENSP00000377971
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000377971
ENSP00000384008
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000384008
ENSP00000384753
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000384753
ENSP00000468845
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000468845
ENSP00000470895
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000470895
ENSP00000498416
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000498416
Sitelinks
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(0 entries)
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(0 entries)
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Multilingual sites
(0 entries)
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