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Centrosomal protein 135
mammalian protein found in Homo sapiens
centrosomal protein 135kDa
centrosome protein cep135
centrosomal protein of 135 kDa
CEP135
centrosomal protein 4
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q66GS9
part of
Centrosomal protein of 135kDa
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q66GS9
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q66GS9
encoded by
CEP135
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q66GS9
molecular function
protein C-terminus binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IPI
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IPI
retrieved
8 April 2019
stated in
Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IPI
retrieved
8 April 2019
stated in
PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IPI
retrieved
8 April 2019
stated in
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IPI
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IEA
centriole
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IEA
retrieved
8 April 2019
stated in
Plk4-induced centriole biogenesis in human cells
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IDA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
TAS
centrosome
determination method
IDA
2 references
retrieved
8 April 2019
stated in
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IDA
retrieved
8 April 2019
stated in
MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IDA
cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IEA
biological process
centriole replication
determination method
IEA
IMP
2 references
retrieved
8 April 2019
stated in
Plk4-induced centriole biogenesis in human cells
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IEA
centriole-centriole cohesion
determination method
IEA
IMP
2 references
retrieved
8 April 2019
stated in
A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IEA
G2/M transition of mitotic cell cycle
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
TAS
positive regulation of non-motile cilium assembly
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IMP
ciliary basal body-plasma membrane docking
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
TAS
regulation of G2/M transition of mitotic cell cycle
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
TAS
positive regulation of establishment of protein localization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
CEP295 interacts with microtubules and is required for centriole elongation
GOA
curator
UniProt
UniProt protein ID
Q66GS9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q66GS9
determination method
IMP
physically interacts with
Viroporin 3a
determination method
Affinity Capture-MS
1 reference
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
Identifiers
RefSeq protein ID
NP_079285
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9662
XP_005265845
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9662
XP_006714118
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9662
XP_011532714
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9662
UniProt protein ID
Q66GS9
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q66GS9
Ensembl protein ID
ENSP00000257287
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000257287
ENSP00000412799
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412799
PDB structure ID
5FCN
1 reference
stated in
UniProt
UniProt protein ID
Q66GS9
retrieved
4 August 2016
language of work or name
English
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