(Q21109783)

English

CLN5 intracellular trafficking protein

mammalian protein found in Homo sapiens

ceroid-lipofuscinosis neuronal protein 5
ceroid-lipofuscinosis, neuronal 5
CLN5

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Statements

1 reference

13 November 2019

Ceroid-lipofuscinosis neuronal protein 5

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75503

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Identification of sites of mannose 6-phosphorylation on lysosomal proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IDA

cell component

perinuclear region of cytoplasm

1 reference

8 April 2019

CLN-1 and CLN-5, genes for infantile and variant late infantile neuronal ceroid lipofuscinoses, are expressed in the embryonic human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IDA

extracellular exosome

1 reference

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75503&geneProductId=UniProtKB:O75503

determination method

IDA

endoplasmic reticulum

1 reference

8 April 2019

Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

8 April 2019

The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

8 April 2019

Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

8 April 2019

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IEA

integral component of membrane

3 references

8 April 2019

CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

8 April 2019

Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IDA

extracellular exosome

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

Identification of sites of mannose 6-phosphorylation on lysosomal proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

CLN-1 and CLN-5, genes for infantile and variant late infantile neuronal ceroid lipofuscinoses, are expressed in the embryonic human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IEP

lysosomal lumen acidification

1 reference

8 April 2019

Elevated lysosomal pH in neuronal ceroid lipofuscinoses (NCLs)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IMP

signal peptide processing

1 reference

8 April 2019

The neuronal ceroid lipofuscinosis protein CLN5: new insights into cellular maturation, transport, and consequences of mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IDA

protein catabolic process

1 reference

8 April 2019

Batten's disease: clues to neuronal protein catabolism in lysosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

CLN-1 and CLN-5, genes for infantile and variant late infantile neuronal ceroid lipofuscinoses, are expressed in the embryonic human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

NAS

retrograde transport, endosome to Golgi

1 reference

8 April 2019

The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IMP

positive regulation of GTP binding

1 reference

8 April 2019

The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

1 reference

8 April 2019

CLN-1 and CLN-5, genes for infantile and variant late infantile neuronal ceroid lipofuscinoses, are expressed in the embryonic human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75503

determination method

IEP

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21109783)

CLN5 intracellular trafficking protein

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