(Q21109799)

English

CDC like kinase 2

mammalian protein found in Homo sapiens

dual specificity protein kinase CLK2
CLK kinase
CLK2
CDC-like kinase 2

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49760

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

8 references

8 April 2019

Phosphorylation of CLK2 at Serine 34 and Threonine 127 by AKT Controls Cell Survival after Ionizing Radiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

The protein interaction landscape of the human CMGC kinase group

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

protein serine/threonine kinase activity

determination method

4 references

8 April 2019

Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

The CLK family kinases, CLK1 and CLK2, phosphorylate and activate the tyrosine phosphatase, PTP-1B

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

protein kinase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

protein serine/threonine/tyrosine kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

determination method

2 references

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

identical protein binding

determination method

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

biological process

regulation of RNA splicing

determination method

1 reference

8 April 2019

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

protein phosphorylation

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

Phosphorylation of CLK2 at Serine 34 and Threonine 127 by AKT Controls Cell Survival after Ionizing Radiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

8 April 2019

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

response to organic substance

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

response to ionizing radiation

determination method

1 reference

8 April 2019

Phosphorylation of CLK2 at Serine 34 and Threonine 127 by AKT Controls Cell Survival after Ionizing Radiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

peptidyl-tyrosine phosphorylation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

response to retinoic acid

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49760

determination method

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49760

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49760

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49760

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000354856

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000354856

ENSP00000357345

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000357345

ENSP00000459461

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000459461

ENSP00000460443

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460443

ENSP00000458788

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458788

ENSP00000347759

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000347759

PDB structure ID

1 reference

UniProt protein ID

22 March 2016

language of work or name

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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