(Q21110108)

Growth factor receptor cysteine-rich domain superfamily

1 reference

Insulin-like growth factor binding protein 3

1 reference

Thyroglobulin type-1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Insulin-like growth factor-binding protein, IGFBP family

1 reference

based on heuristic

inferred from protein domain or family

Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

insulin-like growth factor binding

3 references

8 April 2019

Role of insulin-like growth factor binding protein-3 (IGFBP-3) in the differentiation of primary human adult skeletal myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

protein tyrosine phosphatase activator activity

1 reference

8 April 2019

Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

growth factor binding

1 reference

8 April 2019

insulin-like growth factor I binding

1 reference

27 March 2018

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17936&geneProductId=UniProtKB:P17936

1 reference

8 April 2019

Insulin-like growth factor-independent effects mediated by a C-terminal metal-binding domain of insulin-like growth factor binding protein-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

insulin-like growth factor II binding

NAS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

4 references

8 April 2019

Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

Inhibition of insulin receptor activation by insulin-like growth factor binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

The role of insulin-like growth factor binding protein-3 in the breast cancer cell response to DNA-damaging agents

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

insulin-like growth factor I binding

IPI

insulin-like growth factor ternary complex

1 reference

8 April 2019

Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

insulin-like growth factor binding protein complex

1 reference

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

1 reference

8 April 2019

Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

endoplasmic reticulum lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

Ethnic disparity in the relationship between obesity and plasma insulin-like growth factors: the multiethnic cohort

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

negative regulation of protein phosphorylation

IBA

biological process

1 reference

8 April 2019

The requirement of pax6 for postnatal eye development: evidence from experimental mouse chimeras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

negative regulation of smooth muscle cell proliferation

1 reference

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

negative regulation of smooth muscle cell migration

1 reference

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3

protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

regulation of insulin-like growth factor receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

regulation of glucose metabolic process

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

positive regulation of insulin-like growth factor receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

positive regulation of myoblast differentiation

1 reference

8 April 2019

Role of insulin-like growth factor binding protein-3 (IGFBP-3) in the differentiation of primary human adult skeletal myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

regulation of cell growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

osteoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

positive regulation of apoptotic process

1 reference

8 April 2019

Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

negative regulation of signal transduction

1 reference

8 April 2019

Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

type B pancreatic cell proliferation

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

positive regulation of MAPK cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

negative regulation of cell population proliferation

1 reference

8 April 2019

NKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

post-translational protein modification

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

regulation of phosphoprotein phosphatase activity

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936

Insulin-like growth factor-binding protein, IGFBP

has part(s)

1 reference

Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site

1 reference

Thyroglobulin type-1

1 reference