(Q21110122)

http://www.ebi.ac.uk/interpro/protein/Q13438

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.67.1.1

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Protein OS9-like family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 references

8 April 2019

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

Hrd1p ubiquitin ligase complex

cell component

3 references

8 April 2019

Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

endoplasmic reticulum lumen

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

24 April 2018

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

24 April 2018

Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

24 April 2018

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

endoplasmic reticulum membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

endoplasmic reticulum quality control compartment

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

endoplasmic reticulum

endoplasmic reticulum lumen

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

protein retention in ER lumen

1 reference

8 April 2019

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

negative regulation of retrograde protein transport, ER to cytosol

1 reference

8 April 2019

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK)

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins

protein ubiquitination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

ubiquitin-dependent ERAD pathway

3 references

24 April 2018

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

24 April 2018

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

24 April 2018

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13438&geneProductId=UniProtKB:Q13438

response to endoplasmic reticulum stress

1 reference

8 April 2019

Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

endoplasmic reticulum mannose trimming

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

TAS

transmembrane transport

1 reference

8 April 2019

ubiquitin-dependent protein catabolic process

TAS

1 reference

8 April 2019

Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

ubiquitin-dependent ERAD pathway

4 references

8 April 2019

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

retrograde protein transport, ER to cytosol

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13438

1 reference

InterPro Release 71.0