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Guanylate cyclase 1 soluble subunit alpha 1
mammalian protein found in Homo sapiens
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
guanylate cyclase soluble subunit alpha-3
soluble guanylate cyclase large subunit
GUCY1A1
GC-S-alpha-1
GCS-alpha-3
GCS-alpha-1
guanylate cyclase soluble subunit alpha-1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q02108
part of
Nucleotide cyclase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
NO signalling/Golgi transport ligand-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
H-NOX domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
Heme NO-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Haem NO binding associated domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Adenylyl cyclase class-3/4/guanylyl cyclase family
1 reference
based on heuristic
inferred from protein domain or family
Adenylyl cyclase class-4/guanylyl cyclase, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q02108
encoded by
GUCY1A1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q02108
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
guanylate cyclase activity
determination method
IDA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
Human soluble guanylate cyclase: functional expression and revised isoenzyme family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
retrieved
8 April 2019
stated in
Crystal structures of the catalytic domain of human soluble guanylate cyclase
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IDA
GTP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Crystal structures of the catalytic domain of human soluble guanylate cyclase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IPI
heme binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
lyase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
phosphorus-oxygen lyase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
signaling receptor activity
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Human soluble guanylate cyclase: functional expression and revised isoenzyme family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
TAS
adenylate cyclase activity
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02108&geneProductId=UniProtKB:Q02108
determination method
IBA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
plasma membrane
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02108&geneProductId=UniProtKB:Q02108
determination method
IBA
guanylate cyclase complex, soluble
determination method
TAS
IDA
2 references
retrieved
8 April 2019
stated in
Molecular cloning of the cDNAs coding for the two subunits of soluble guanylyl cyclase from human brain
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
TAS
retrieved
8 April 2019
stated in
Crystal structures of the catalytic domain of human soluble guanylate cyclase
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IDA
glutamatergic synapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
GABA-ergic synapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
biological process
intracellular signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
cyclic nucleotide biosynthetic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
blood circulation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Human soluble guanylate cyclase: functional expression and revised isoenzyme family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
TAS
regulation of blood pressure
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
cGMP biosynthetic process
determination method
IDA
IEA
4 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
retrieved
8 April 2019
stated in
Crystal structures of the catalytic domain of human soluble guanylate cyclase
GOA
curator
UniProt
UniProt protein ID
Q02108
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IDA
relaxation of vascular associated smooth muscle
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
nitric oxide mediated signal transduction
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Human soluble guanylate cyclase: functional expression and revised isoenzyme family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
TAS
positive regulation of nitric oxide mediated signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02108
determination method
IEA
has part(s)
Adenylyl cyclase class-4/guanylyl cyclase, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
Adenylyl cyclase class-3/4/guanylyl cyclase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
Heme NO-binding
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
Haem NO binding associated
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q02108
Identifiers
RefSeq protein ID
NP_000847
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001124154
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001124155
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001124156
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001124157
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001124159
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001243378
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
XP_005263013
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
XP_005263014
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
XP_011530202
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366595
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366596
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366597
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366598
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366599
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366600
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366601
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366602
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366603
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366604
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
NP_001366605
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2982
UniProt protein ID
Q02108
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q02108
Ensembl protein ID
ENSP00000296518
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000296518
ENSP00000412201
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412201
ENSP00000421493
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421493
ENSP00000424361
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000424361
ENSP00000426040
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426040
ENSP00000426968
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426968
ENSP00000377418
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000377418
ENSP00000409903
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000409903
ENSP00000422141
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422141
ENSP00000424863
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000424863
ENSP00000479710
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000479710
PDB structure ID
3UVJ
1 reference
stated in
UniProt
UniProt protein ID
Q02108
retrieved
9 August 2016
language of work or name
English
4NI2
1 reference
stated in
UniProt
UniProt protein ID
Q02108
retrieved
9 August 2016
language of work or name
English
Sitelinks
Wikipedia
(0 entries)
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Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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