(Q21110359)

http://www.ebi.ac.uk/interpro/protein/Q02153

NO signalling/Golgi transport ligand-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02153

H-NOX domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02153

Heme NO-binding domain, protein family

1 reference

Haem NO binding associated domain, protein family

1 reference

Adenylyl cyclase class-3/4/guanylyl cyclase family

1 reference

Adenylyl cyclase class-4/guanylyl cyclase, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

guanylate cyclase activity

4 references

8 April 2019

Human soluble guanylate cyclase: functional expression and revised isoenzyme family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

8 April 2019

Crystal structures of the catalytic domain of human soluble guanylate cyclase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

1 reference

8 April 2019

Crystal structures of the catalytic domain of human soluble guanylate cyclase

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

phosphorus-oxygen lyase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

signaling receptor activity

1 reference

8 April 2019

Human soluble guanylate cyclase: functional expression and revised isoenzyme family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

adenylate cyclase activity

TAS

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02153&geneProductId=UniProtKB:Q02153

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02153&geneProductId=UniProtKB:Q02153

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

presynaptic active zone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

intracellular signal transduction

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

cyclic nucleotide biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

1 reference

8 April 2019

Human soluble guanylate cyclase: functional expression and revised isoenzyme family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

nitric oxide-cGMP-mediated signaling pathway

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

cGMP biosynthetic process

ISS

IDA

nitric oxide mediated signal transduction

3 references

1 reference

8 April 2019

Human soluble guanylate cyclase: functional expression and revised isoenzyme family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

cellular response to nitric oxide

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

ISS

cGMP-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

trans-synaptic signaling by nitric oxide, modulating synaptic transmission

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02153

physically interacts with

IBA

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL730

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL6622

pentaerythritol tetranitrate

object has role

activation

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL466659

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200689

riociguat

object has role

positive allosteric modullator

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2107834

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2107729

sodium nitroprusside dihydrate

object has role

activation

1 reference

14 August 2023