(Q21110695)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

Cloning of three novel neuronal Cdk5 activator binding proteins

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

IPI

gamma-tubulin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

CDK5RAP2 is required for spindle checkpoint function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

13 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Proteomic characterization of the human centrosome by protein correlation profiling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

CDK5RAP2 is required for spindle checkpoint function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

pericentriolar material

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

1 reference

8 April 2019

Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

perinuclear region of cytoplasm

1 reference

8 April 2019

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

regulation of neuron differentiation

HDA

biological process

1 reference

8 April 2019

Cloning of three novel neuronal Cdk5 activator binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

negative regulation of neuron differentiation

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

CDK5RAP2 is required for spindle checkpoint function

IEA

chromosome segregation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

CDK5RAP2 is required for spindle checkpoint function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

3 references

8 April 2019

Identification of a common protein association region in the neuronal Cdk5 activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

G2/M transition of mitotic cell cycle

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

microtubule bundle formation

TAS

1 reference

8 April 2019

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

regulation of spindle checkpoint

1 reference

17 October 2017

CDK5RAP2 is required for spindle checkpoint function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96SN8&geneProductId=UniProtKB:Q96SN8

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication

centriole replication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

microtubule organizing center organization

1 reference

8 April 2019

Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

microtubule cytoskeleton organization

1 reference

8 April 2019

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

ciliary basal body-plasma membrane docking

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

1 reference

8 April 2019

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

regulation of G2/M transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

positive regulation of microtubule polymerization

TAS

1 reference

8 April 2019

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

regulation of mitotic cell cycle spindle assembly checkpoint

1 reference

8 April 2019

CDK5RAP2 is required for spindle checkpoint function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SN8

physically interacts with

1 reference

https://thebiogrid.org/news/227

retrieved

19 April 2020

stated in

BioGRID

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

has part(s)

Centrosomin, N-terminal motif 1

1 reference

stated in

InterPro Release 71.0