(Q21111061)

http://www.ebi.ac.uk/interpro/protein/P40305

IFI6/IFI27-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40305

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

identical protein binding

ND

1 reference

8 April 2019

Apoptotic properties of the type 1 interferon induced family of human mitochondrial membrane ISG12 proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

mitochondrial outer membrane

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors

TAS

nuclear inner membrane

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

1 reference

8 April 2019

The interferon alpha induced protein ISG12 is localized to the nuclear membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a

mitochondrial membranes

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

endoplasmic reticulum

1 reference

8 April 2019

endoplasmic reticulum membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

apoptotic signaling pathway

biological process

1 reference

16 July 2018

Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

activation of cysteine-type endopeptidase activity involved in apoptotic process

IGI

1 reference

16 July 2018

Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

type I interferon signaling pathway

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

regulation of protein export from nucleus

TAS

1 reference

8 April 2019

The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

proteasome-mediated ubiquitin-dependent protein catabolic process

IBA

1 reference

8 April 2019

ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

modulation by host of viral genome replication

1 reference

8 April 2019

ISG12a inhibits HCV replication and potentiates the anti-HCV activity of IFN-α through activation of the Jak/STAT signaling pathway independent of autophagy and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway

innate immune response

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

defense response to virus

2 references

10 September 2018

ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

10 September 2018

ISG12a inhibits HCV replication and potentiates the anti-HCV activity of IFN-α through activation of the Jak/STAT signaling pathway independent of autophagy and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

protein K48-linked ubiquitination

1 reference

8 April 2019

ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

apoptotic signaling pathway

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40305&geneProductId=UniProtKB:P40305

extrinsic apoptotic signaling pathway

IBA

1 reference

8 April 2019

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

immune system process

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

defense response to virus

3 references

8 April 2019

ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

8 April 2019

ISG12a inhibits HCV replication and potentiates the anti-HCV activity of IFN-α through activation of the Jak/STAT signaling pathway independent of autophagy and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40305