(Q21111244)

http://www.ebi.ac.uk/interpro/protein/O95994

1 reference

13 November 2019

1 reference

13 November 2019

epidermal growth factor receptor binding

1 reference

8 April 2019

Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

7 references

8 April 2019

hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

protein homodimerization activity

IPI

1 reference

27 March 2018

hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

IEA

endoplasmic reticulum

4 references

27 March 2018

27 March 2018

AGR2 gene function requires a unique endoplasmic reticulum localization motif

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

IEA

endoplasmic reticulum

5 references

8 April 2019

8 April 2019

AGR2 gene function requires a unique endoplasmic reticulum localization motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

positive regulation of PERK-mediated unfolded protein response

IBA

biological process

1 reference

8 April 2019

Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

response to endoplasmic reticulum stress

IDA

1 reference

8 April 2019

Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

positive regulation of IRE1-mediated unfolded protein response

1 reference

8 April 2019

Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

positive regulation of gene expression

IDA

1 reference

8 April 2019

AGR2 gene function requires a unique endoplasmic reticulum localization motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

negative regulation of cell death

1 reference

27 March 2018

Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

positive regulation of epidermal growth factor receptor signaling pathway

1 reference

8 April 2019

Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

lung goblet cell differentiation

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

positive regulation of cell-substrate adhesion

IEA

1 reference

8 April 2019

Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95994&geneProductId=UniProtKB:O95994

positive regulation of protein localization to plasma membrane

IBA

1 reference

8 April 2019

Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95994