(Q21111598)

English

Sorting nexin 5

mammalian protein found in Homo sapiens

SNX5
sorting nexin-5

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

dynactin binding

determination method

1 reference

8 April 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

protein binding

determination method

3 references

9 May 2019

LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

phosphatidylinositol binding

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

8 April 2019

Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

protein heterodimerization activity

determination method

1 reference

9 May 2019

Retromer: Structure, function, and roles in mammalian disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

cadherin binding

determination method

1 reference

27 March 2018

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5X3&geneProductId=UniProtKB:Q9Y5X3

determination method

phosphatidylinositol-5-phosphate binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

D1 dopamine receptor binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

phosphatidylinositol-4-phosphate binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

phosphatidylinositol-3,5-bisphosphate binding

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

cadherin binding

determination method

1 reference

9 May 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

phosphatidylinositol binding

determination method

5 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

cell projection

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

retromer, tubulation complex

determination method

1 reference

9 May 2019

Retromer: Structure, function, and roles in mammalian disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

extrinsic component of cytoplasmic side of plasma membrane

determination method

extrinsic component of endosome membrane

determination method

1 reference

9 May 2019

Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

tubular endosome

determination method

1 reference

9 May 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

retromer complex

determination method

1 reference

9 May 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

cytoplasmic vesicle membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

macropinocytic cup

determination method

1 reference

9 May 2019

A role for SNX5 in the regulation of macropinocytosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

cytoplasmic vesicle

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

3 references

biological process

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

vesicle organization

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5X3&geneProductId=UniProtKB:Q9Y5X3

determination method

protein transport

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

intracellular protein transport

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

regulation of macroautophagy

determination method

1 reference

9 May 2019

Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in Drosophila

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

epidermal growth factor catabolic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

positive regulation of renal sodium excretion

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

negative regulation of blood pressure

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

A role for SNX5 in the regulation of macropinocytosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

retrograde transport, endosome to Golgi

determination method

3 references

9 May 2019

Retromer: Structure, function, and roles in mammalian disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5X3

determination method

Phox homologous domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5X3

Sorting nexin Vps5-like, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5X3

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000366988

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366988

ENSP00000366998

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366998

ENSP00000475510

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475510

ENSP00000404448

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000404448

ENSP00000406731

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000406731

ENSP00000475606

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475606

ENSP00000475983

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475983

ENSP00000476097

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476097

ENSP00000479021

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000479021

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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