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Pyrin domain containing 2
mammalian protein found in Homo sapiens
cPOP2
pyrin domain-containing protein 2
pyrin-only protein 2
cellular POP2
PYDC2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q56P42
part of
Death-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q56P42
DAPIN domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q56P42
encoded by
PYDC2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q56P42
molecular function
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IPI
cell component
cytoplasm
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IEA
retrieved
8 April 2019
stated in
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IDA
retrieved
8 April 2019
stated in
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IDA
nucleus
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IEA
retrieved
8 April 2019
stated in
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IDA
retrieved
8 April 2019
stated in
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IDA
biological process
negative regulation of signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IEA
innate immune response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IEA
inflammatory response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IEA
negative regulation of NLRP3 inflammasome complex assembly
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
retrieved
8 April 2019
stated in
The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
negative regulation of NF-kappaB transcription factor activity
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
retrieved
8 April 2019
stated in
The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
negative regulation of inflammatory response
determination method
IMP
2 references
retrieved
8 April 2019
stated in
The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
retrieved
8 April 2019
stated in
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
negative regulation of tumor necrosis factor-mediated signaling pathway
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
retrieved
8 April 2019
stated in
The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
immune system process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IEA
negative regulation of NIK/NF-kappaB signaling
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
GOA
curator
UniProt
UniProt protein ID
Q56P42
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q56P42
determination method
IMP
has part(s)
DAPIN domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q56P42
Identifiers
RefSeq protein ID
NP_001076777
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
152138
UniProt protein ID
Q56P42
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q56P42
Ensembl protein ID
ENSP00000492367
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000492367
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