(Q21111945)

English

Collagen type XXV alpha 1 chain

mammalian protein found in Homo sapiens

COL25A1
alzheimer disease amyloid-associated protein
collagen alpha-1(XXV) chain
collagen-like Alzheimer amyloid plaque component
CLAC-P
collagenous Alzheimer amyloid plaque component
AMY

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Statements

1 reference

13 November 2019

collagen triple helix repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

4 references

8 April 2019

Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

8 April 2019

CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

8 April 2019

CLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

8 April 2019

Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

determination method

IDA

extracellular matrix structural constituent

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

8 April 2019

Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

determination method

IBA

extracellular matrix structural constituent conferring tensile strength

determination method

IEA

RCA

extracellular matrix structural constituent conferring tensile strength

1 reference

8 April 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

determination method

IEA

endoplasmic reticulum lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

1 reference

24 April 2018

CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BXS0&geneProductId=UniProtKB:Q9BXS0

determination method

IDA

integral component of plasma membrane

1 reference

8 April 2019

CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

determination method

IBA

collagen-containing extracellular matrix

1 reference

8 April 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BXS0

determination method

HDA

has part(s)

Collagen triple helix repeat

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BXS0

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

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30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

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1 reference

1 reference

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0 references

(Q21111945)

Collagen type XXV alpha 1 chain

Statements

Identifiers

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