(Q21112346)

WD40-repeat-containing domain superfamily

1 reference

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

G-protein beta WD-40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

ATP-dependent activity, acting on DNA

1 reference

9 May 2019

Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II

DNA helicase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

ubiquitin-protein transferase activity

1 reference

21 June 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

5 references

9 May 2019

Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

protein-containing complex binding

IPI

1 reference

9 May 2019

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

ubiquitin-protein transferase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

nucleotide-excision repair complex

TAS

1 reference

21 June 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

1 reference

9 May 2019

Translocation of Cockayne syndrome group A protein to the nuclear matrix: possible relevance to transcription-coupled DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

Cul4A-RING E3 ubiquitin ligase complex

1 reference

21 June 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

Translocation of Cockayne syndrome group A protein to the nuclear matrix: possible relevance to transcription-coupled DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

Cul4-RING E3 ubiquitin ligase complex

1 reference

9 May 2019

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

protein-containing complex

1 reference

9 May 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

Cul4A-RING E3 ubiquitin ligase complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

protein polyubiquitination

1 reference

21 June 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

positive regulation of DNA repair

1 reference

21 June 2018

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

proteasome-mediated ubiquitin-dependent protein catabolic process

IMP

1 reference

21 June 2018

CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

protein ubiquitination

1 reference

9 May 2019

protein autoubiquitination

1 reference

9 May 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

transcription-coupled nucleotide-excision repair

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

21 June 2018

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

21 June 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

response to oxidative stress

3 references

21 June 2018

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

21 June 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13216&geneProductId=UniProtKB:Q13216

nucleotide-excision repair

1 reference

9 May 2019

The role of CSA in the response to oxidative DNA damage in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

post-translational protein modification

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

response to auditory stimulus

TAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

response to organic cyclic compound

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

protein polyubiquitination

IBA

transcription-coupled nucleotide-excision repair

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

8 April 2019

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

8 April 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

proteasome-mediated ubiquitin-dependent protein catabolic process

IBA

IBA

transcription-coupled nucleotide-excision repair

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13216

1 reference

G-protein beta WD-40 repeat

1 reference

WD40 repeat, conserved site

1 reference