(Q21112763)

English

NOC2 like nucleolar associated transcriptional repressor

mammalian protein found in Homo sapiens

NOC2L
protein NOC2 homolog
nucleolar complex associated 2 homolog
nucleolar complex protein 2 homolog
NOC2L nucleolar associated transcriptional repressor
novel INHAT (inhibitor of histone acetyltransferase) repressor
novel INHAT repressor
NOC2-like protein
protein phosphatase 1, regulatory subunit 12

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Statements

1 reference

13 November 2019

Nucleolar complex protein 2

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9Y3T9

Armadillo-type fold

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9Y3T9

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

26 September 2017

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

1 reference

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

5 references

8 April 2019

Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IPI

transcription corepressor activity

1 reference

26 September 2017

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

26 September 2017

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

26 September 2017

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IBA

biological process

cellular response to UV

1 reference

8 April 2019

Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IDA

negative regulation of B cell apoptotic process

1 reference

8 April 2019

Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IMP

negative regulation of histone acetylation

1 reference

26 September 2017

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method

IDA

negative regulation of transcription by RNA polymerase II

determination method

IDA

2 references

regulation of transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method

IEA

transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method

IEA

negative regulation of intrinsic apoptotic signaling pathway

1 reference

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IEA

ribosomal large subunit biogenesis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IBA

regulation of signal transduction by p53 class mediator

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

TAS

negative regulation of transcription by RNA polymerase II

3 references

8 April 2019

Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method

IBA

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

(Q21112763)

NOC2 like nucleolar associated transcriptional repressor

Statements

Identifiers

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