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ELL associated factor 2
mammalian protein found in Homo sapiens
EAF2
ELL-associated factor 2
testosterone-regulated apoptosis inducer and tumor suppressor protein
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96CJ1
part of
EAF family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96CJ1
Transcription elognation factor Eaf, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96CJ1
encoded by
EAF2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96CJ1
molecular function
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IDA
RNA polymerase II transcription regulatory region sequence-specific DNA binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IDA
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IPI
retrieved
8 April 2019
stated in
FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IPI
retrieved
8 April 2019
stated in
EAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IPI
cell component
nuclear speck
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96CJ1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
transcription elongation factor complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The little elongation complex regulates small nuclear RNA transcription
GOA
curator
UniProt
UniProt protein ID
Q96CJ1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IDA
super elongation complex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96CJ1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
nucleoplasm
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
biological process
positive regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
negative regulation of cell growth
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
negative regulation of epithelial cell proliferation involved in prostate gland development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
positive regulation of transcription by RNA polymerase II
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IDA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q96CJ1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96CJ1&geneProductId=UniProtKB:Q96CJ1
determination method
IEA
apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96CJ1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
IEA
transcription by RNA polymerase II
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
TAS
transcription elongation from RNA polymerase II promoter
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96CJ1
determination method
TAS
exact match
https://identifiers.org/uniprot:Q96CJ1
1 reference
stated in
Identifiers.org
UniProt protein ID
Q96CJ1
reference URL
https://registry.identifiers.org/registry/uniprot
http://purl.uniprot.org/uniprot/Q96CJ1
1 reference
stated in
Identifiers.org
UniProt protein ID
Q96CJ1
reference URL
https://registry.identifiers.org/registry/uniprot
https://www.ncbi.nlm.nih.gov/protein/Q96CJ1
1 reference
stated in
Identifiers.org
UniProt protein ID
Q96CJ1
reference URL
https://registry.identifiers.org/registry/uniprot
has part(s)
Transcription elognation factor Eaf, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96CJ1
Identifiers
RefSeq protein ID
NP_001306970
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55840
NP_060926
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55840
XP_005247675
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55840
XP_016862350
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55840
XP_016862351
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55840
XP_016862352
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55840
UniProt protein ID
Q96CJ1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96CJ1
Ensembl protein ID
ENSP00000273668
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000273668
ENSP00000410708
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000410708
ENSP00000418374
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000418374
ENSP00000419552
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000419552
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