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(Q21113057)
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English
Cripto, FRL-1, cryptic family 1
mammalian protein found in Homo sapiens
CFC1
cryptic family protein 1
heterotaxy 2 (autosomal dominant)
cryptic protein
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P0CG37
part of
Cryptic/Cripto, CFC domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P0CG37
encoded by
CFC1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P0CG37
molecular function
nodal binding
determination method
IPI
1 reference
retrieved
16 July 2018
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P0CG37&geneProductId=UniProtKB:P0CG37
determination method
IPI
molecular function
determination method
ND
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
ND
signaling receptor binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
nodal binding
determination method
IBA
IPI
2 references
retrieved
8 April 2019
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
activin receptor binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P0CG37&geneProductId=UniProtKB:P0CG37
determination method
IEA
anchored component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IEA
cellular component
determination method
ND
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
ND
extracellular region
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
cell surface
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IEA
determination of left/right symmetry
determination method
NAS
1 reference
retrieved
16 July 2018
stated in
Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P0CG37&geneProductId=UniProtKB:P0CG37
determination method
NAS
gastrulation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IEA
nodal signaling pathway
determination method
IMP
1 reference
retrieved
16 July 2018
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P0CG37&geneProductId=UniProtKB:P0CG37
determination method
IMP
determination of left/right symmetry
determination method
IBA
NAS
2 references
retrieved
8 April 2019
stated in
Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
NAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
heart development
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
anterior/posterior pattern specification
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
BMP signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
nodal signaling pathway
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
GOA
curator
UniProt
UniProt protein ID
P0CG37
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
anatomical structure development
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0CG37
determination method
IBA
has part(s)
EGF-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P0CG37
Cryptic/Cripto, CFC domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P0CG37
EGF-like, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P0CG37
Identifiers
RefSeq protein ID
NP_001257349
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55997
NP_001257350
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55997
NP_115934
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55997
XP_011509788
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
55997
UniProt protein ID
P0CG37
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P0CG37
Ensembl protein ID
ENSP00000259216
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000259216
ENSP00000480526
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000480526
ENSP00000480843
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000480843
Sitelinks
Wikipedia
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Wikiquote
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Multilingual sites
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