(Q21113152)

http://www.ebi.ac.uk/interpro/protein/P36382

Connexin, C-terminal

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P36382

Connexin, N-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P36382

Gap junction alpha-5 protein (Cx40), C-terminal domain, protein family

1 reference

Connexin, N-terminal domain, protein family

1 reference

Gap junction protein family

1 reference

Connexin, conserved site, protein family

1 reference

gap junction channel activity involved in cardiac conduction electrical coupling

1 reference

13 November 2019

1 reference

13 November 2019

gap junction channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling

1 reference

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

gap junction hemi-channel activity

1 reference

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling

4 references

8 April 2019

Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling

1 reference

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling

1 reference

8 April 2019

Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

disordered domain specific binding

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

integral component of membrane

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

integral component of plasma membrane

1 reference

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

4 references

8 April 2019

Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

bundle of His cell to Purkinje myocyte communication by electrical coupling

biological process

1 reference

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

skeletal system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of ventricular cardiac muscle cell membrane depolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

cardiac conduction system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

ventricular septum development

1 reference

8 April 2019

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

negative regulation of blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

ventricular septum morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

SA node cell action potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

AV node cell to bundle of His cell communication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of atrial cardiac muscle cell membrane depolarization

3 references

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

ventricular cardiac muscle cell action potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

cell communication by electrical coupling involved in cardiac conduction

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

outflow tract morphogenesis

1 reference

8 April 2019

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

atrial ventricular junction remodeling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

cell communication by electrical coupling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

mitral valve development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

pulmonary valve formation

1 reference

8 April 2019

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

embryonic heart tube development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of Purkinje myocyte action potential

1 reference

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

atrial septum morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

potassium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of renin secretion into blood stream

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

blood vessel development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

embryonic limb morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

protein complex oligomerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

positive regulation of vasoconstriction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

IEP

transmembrane transport

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

endothelium development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

renal system process involved in regulation of systemic arterial blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of systemic arterial blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

gap junction assembly

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

positive regulation of cell communication by chemical coupling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

cell communication involved in cardiac conduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of cardiac muscle contraction

3 references

8 April 2019

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

septum primum development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of heart rate by cardiac conduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

negative regulation of glomerular filtration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

atrial septum development

1 reference

8 April 2019

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

foramen ovale closure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

cell communication by chemical coupling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of atrial cardiac muscle cell action potential

1 reference

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of ventricular cardiac muscle cell membrane repolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

regulation of membrane depolarization during cardiac muscle cell action potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

atrial cardiac muscle cell to AV node cell communication by electrical coupling

5 references

8 April 2019

Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling

1 reference

8 April 2019

Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

blood vessel diameter maintenance

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36382

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4151

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2447

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4278

language of work or name

English

retrieved

17 August 2016

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

Transporter Classification Database ID

1.A.24.1.5

1 reference