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Gap junction protein gamma 2
mammalian protein found in Homo sapiens
connexin-46.6
connexin-47
gap junction alpha-12 protein
gap junction gamma-2 protein
GJC2
Cx47
gap junction protein, gamma 2, 47kDa
Cx46.6
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q5T442
part of
Connexin, N-terminal domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q5T442
connexins
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q5T442
Connexin, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Gap junction protein family
1 reference
based on heuristic
inferred from protein domain or family
Connexin, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q5T442
encoded by
GJC2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q5T442
molecular function
gap junction channel activity
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
gap junction channel activity involved in cell communication by electrical coupling
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Loss-of-function GJA12/Connexin47 mutations cause Pelizaeus-Merzbacher-like disease
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IMP
cell component
integral component of membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
myelin sheath
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
cell junction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
plasma membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
connexin complex
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
gap junction
determination method or standard
IEA
IMP
3 references
retrieved
8 April 2019
stated in
Loss-of-function GJA12/Connexin47 mutations cause Pelizaeus-Merzbacher-like disease
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
paranode region of axon
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
soma
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
perikaryon
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
proximal neuron projection
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
biological process
cell communication
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
cell-cell signaling
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
response to toxic substance
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
transmembrane transport
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
cell communication by electrical coupling
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Loss-of-function GJA12/Connexin47 mutations cause Pelizaeus-Merzbacher-like disease
GOA
curator
UniProt
UniProt protein ID
Q5T442
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IMP
regulation of protein phosphorylation
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
brain development
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
positive regulation of gene expression
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
positive regulation of oligodendrocyte progenitor proliferation
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
positive regulation of calcium ion transmembrane transport
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
negative regulation of G1/S transition of mitotic cell cycle
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5T442
determination method or standard
IEA
physically interacts with
carbenoxolone
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4151
language of work or name
English
retrieved
17 August 2016
flufenamic acid
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2447
language of work or name
English
retrieved
17 August 2016
1-octanol
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4278
language of work or name
English
retrieved
17 August 2016
has part(s)
Gap junction protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q5T442
Connexin, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q5T442
Connexin, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q5T442
Identifiers
RefSeq protein ID
NP_065168
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57165
UniProt protein ID
Q5T442
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q5T442
Ensembl protein ID
ENSP00000355675
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000355675
Transporter Classification Database ID
1.A.24.2.1
1 reference
based on heuristic
TCDB BLAST
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