(Q21113425)

English

Interleukin 34

mammalian protein found in Homo sapiens

IL34
interleukin-34

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6ZMJ4

Interleukin-34 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6ZMJ4

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

cytokine activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

growth factor activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

protein binding

determination method

identical protein binding

determination method

1 reference

27 February 2018

Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZMJ4&geneProductId=UniProtKB:Q6ZMJ4

determination method

macrophage colony-stimulating factor receptor binding

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

extracellular space

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

8 April 2019

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

extracellular space

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

biological process

positive regulation of monocyte differentiation

determination method

1 reference

8 April 2019

IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

positive regulation of macrophage differentiation

determination method

1 reference

8 April 2019

IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

innate immune response

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

inflammatory response

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

immune system process

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

cytokine-mediated signaling pathway

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

microglial cell proliferation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

positive regulation of gene expression

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

positive regulation of cell population proliferation

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZMJ4

determination method

positive regulation of macrophage differentiation

determination method

positive regulation of monocyte differentiation

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000288098

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000288098

ENSP00000397863

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397863

ENSP00000455240

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455240

ENSP00000463886

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463886

PDB structure ID

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

UniProt protein ID

29 June 2016

language of work or name

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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