(Q21113736)

Metallopeptidase, catalytic domain superfamily

1 reference

Peptidase M12B, ADAM/reprolysin, protein family

1 reference

Reprolysin domain, adamalysin-type, protein family

1 reference

ADAM, cysteine-rich, protein family

1 reference

Disintegrin domain, protein family

1 reference

EGF-like domain, protein family

1 reference

Disintegrin, conserved site, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

Peptidase M12B, propeptide family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23

protein self-association

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

3 references

8 April 2019

FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

metalloendopeptidase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

serine-type endopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

metallopeptidase activity

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

Involvement of a disintegrin and a metalloproteinase 8 (ADAM8) in osteoclastogenesis and pathological bone destruction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex

1 reference

8 April 2019

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

integral component of plasma membrane

1 reference

8 April 2019

Involvement of a disintegrin and a metalloproteinase 8 (ADAM8) in osteoclastogenesis and pathological bone destruction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

dense core granule membrane

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

specific granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

tertiary granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

ficolin-1-rich granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

positive regulation of inflammatory response

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

extracellular matrix disassembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

2 references

positive regulation of cellular extravasation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

positive regulation of neutrophil extravasation

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

positive regulation of protein processing

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

regulation of cell-cell adhesion

NAS

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

positive regulation of protein secretion

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

IC

inflammatory response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

cellular response to hypoxia

1 reference

8 April 2019

Hypoxia-dependent expression of ADAM8 in human pancreatic cancer cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

positive regulation of T cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

positive regulation of membrane protein ectodomain proteolysis

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

neutrophil degranulation

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78325

Peptidase M12B, ADAM/reprolysin

has part(s)

1 reference

EGF-like, conserved site

1 reference

ADAM, cysteine-rich

1 reference

Disintegrin domain

1 reference

Disintegrin, conserved site

1 reference

Peptidase M12B, propeptide

1 reference

EGF-like domain

1 reference

Reprolysin domain, adamalysin-type

1 reference