(Q21113744)

English

Eukaryotic translation initiation factor 2B subunit alpha

mammalian protein found in Homo sapiens

translation initiation factor eIF-2B subunit alpha
eIF-2B GDP-GTP exchange factor subunit alpha
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa

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Statements

1 reference

13 November 2019

NagB/RpiA transferase-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q14232

Initiation factor 2B-related

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q14232

1 reference

13 November 2019

1 reference

13 November 2019

guanyl-nucleotide exchange factor activity

1 reference

8 April 2019

Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IDA

identical protein binding

1 reference

9 May 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IPI

translation initiation factor activity

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

9 May 2019

An efficient mammalian cell-free translation system supplemented with translation factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

1 reference

9 May 2019

A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

1 reference

9 May 2019

A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IDA

eukaryotic translation initiation factor 2B complex

determination method

IDA

eukaryotic translation initiation factor 2B complex

3 references

9 May 2019

Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

9 May 2019

Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IBA

biological process

response to peptide hormone

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IEA

oligodendrocyte development

1 reference

9 May 2019

The life and death of oligodendrocytes in vanishing white matter disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IEA

T cell receptor signaling pathway

1 reference

9 May 2019

T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IDA

translational initiation

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

9 May 2019

An efficient mammalian cell-free translation system supplemented with translation factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IBA

regulation of translational initiation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14232

determination method

IBA

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

English

(Q21113744)

Eukaryotic translation initiation factor 2B subunit alpha

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